Intraspinal epidural nerve root transplantation for lower extremity motor dysfunction after thoracolumbar spinal cord injury

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200060473

Enrollment

Unknown

Registered

2022-06-02

Start date

2022-05-23

Completion date

Unknown

Last updated

2024-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower extremity dysfunction after paraplegia

Interventions

Experimental group:The anterior and posterior roots of two of the five levels from T9 to L1, and the anterior and posterior roots of L2 and L3 were anastomosed

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-65 years; 2. Paraplegia after thoracolumbar spinal cord injury (ASIA A, B), no neurological impairment at T10 level and above; 3. Mainly manifested as motor dysfunction of both lower extremities; 4. Patients with spinal cord injury within 2 years.

Exclusion criteria

Exclusion criteria: Have diabetes, heart and lung disease, developmental delay, poor cognitive ability, severe fixed contracture or joint deformity of the lower extremities and other systemic diseases.

Design outcomes

Primary

Measure	Time frame
MMT unarmed muscle strength assessment;Modified Ashworth classification;Holden walking ability rating;Gait analysis;EMG;	—

Countries

China

Contacts

Public ContactCao Xiaojian

The First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital)

xiaojiancao001@163.com+86 13002505801

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026