depression
Conditions
Interventions
control group:Enhanced conventioal therapy
experimental group:PM+ psychological therapy intervention
Sponsors
Shenzhen Kangning Hospital
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Hospital inclusion criteria: (1) Aged 12-18 years, years of education >=5 years; (2) Meet the diagnostic criteria for major depressive disorder of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5); (3) Use MINI screening to exclude other mental disorders; (4) Subjects and their families agree to participate in the program and sign informed consent. 2. School inclusion criteria: (1) PHQ-9>=5, but did not meet the DSM-5 diagnostic criteria for depression; (2) Aged 12-18 years; (3) Years of education >= 6 years; (4) No previous history of mental disorders; (5) Subject and family members agree to participate in the program and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with severe physical diseases (such as cardiovascular, liver, kidney, gastrointestinal diseases, etc.), infectious diseases and immune system diseases; 2. Patients with traumatic brain injury, epilepsy or other known severe neurological diseases or organic brain diseases; 3. Patients with a history of severe mental disorders such as schizophrenia or mental retardation; 4. Dependent on or abusing alcohol or other substances or taking antipsychotics, central stimulants, etc.; 5. Patients at high risk of suicide; 6. Patients with contraindications for MRI examination, such as pregnant or lactating women, or those planning to become pregnant, patients with cardiac pacemakers, patients with aneurysm clips after cranial surgery, patients with ferromagnetic implants, patients with artificial metal valves after cardiac surgery, patients with alloy prostheses or metal joints, patients with insulin pumps or nerve stimulators in the body, etc.; 7. Patients with contraindications for EEG examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression severity;Non-suicidal self-injury behavior;Suicidal ideation;Rumination;Functional magnetic resonance imaging;EEG; | — |
Secondary
| Measure | Time frame |
|---|---|
| Childhood trauma;Self dignity;Emotion regulation;Recognition;Depression external appearance; | — |
Countries
China
Contacts
Public ContactZhou Yongjie
Shenzhen Kangning Hospital
Outcome results
None listed