Lung cancer surgery and anesthesia
Conditions
Interventions
Group 1 :OFA + non-intubation
Group 2:OBA + non-intubation
Group 3:OFA + intubation
Group 4:OBA + intubation
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old; 2. ASA Grade I-III; 3. The operation is limited to a single lobe of the lung; 4. Elective thoracoscopic lung resection.
Exclusion criteria
Exclusion criteria: 1. Body mass index (BMI) >= 28.0 kg/m2, obstructive sleep apnea syndrome, or anticipated difficult intubation (modified Mallampati grade 4); 2. Chronic pulmonary disease, history of thoracic surgery; 3. Cancer distant metastasis; 4. Left ventricular ejection fraction < 40%, second-degree or greater atrioventricular block, sick sinus syndrome; 5. Liver dysfunction (Child-Pugh grade C), need for renal replacement therapy; 6. Cerebrovascular disease, Alzheimer disease, Parkinson disease, epilepsy; 7. Alcohol misuse, pre-existing chronic pain; 8. Hypersensitivity to study medications, 9. Inability to understand the scales in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feasibility of this study;Quality of recovery after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of recovery after surgery;Pain scores at rest;Pain scores on coughing;Patient-controlled sufentanil consumption;Semiquantitative cough strength score;Nausea and vomiting;Length of postoperative hospital stay;Healthcare cost;Comprehensive complication index (CCI) score;Quality of life;Length of PACU stay;30-day mortality; | — |
Countries
China
Contacts
Public ContactShaomu Chen
The First Affiliated Hospital of Soochow University
Outcome results
None listed