Lymphoma
Conditions
Interventions
Group 1 :
Group 2:
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old; 2. The pathological biopsy diagnosis is in line with diffuse large B-cell lymphoma or high-grade B-cell lymphoma according to the WHO2016 classification criteria; 3. High-throughput sequencing of pathological tissue or peripheral blood conforms to MCD subtype; 4. PET examination shows that there are >= 2 extranodal organ involvement (except central nervous system involvement); 5. Measurable lesions on cross-sectional imaging (defined as the presence of at least 1 bilateral Vickers measurable lesions, regardless of short-axis diameter); 6. Eastern Cooperative Oncology Group (ECOG) physical status = 35 mL/min; 8. Voluntary participation, willing to provide the above treatment data, signed and dated informed consent.
Exclusion criteria
Exclusion criteria: 1. Has been enrolled in other clinical trials; 2. Immunosuppressive therapy is being used for other diseases; 3. Have received other treatments for lymphoma before enrollment; 4. Combined with other malignant tumors; 5. The researcher judges that he is not suitable to participate in this research; 6. Severe mental or nervous system disorders, affecting informed consent and/or adverse reaction expression or observation; 7. Patients who cannot be followed up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total effective rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-free survival rate;Overall survival rate; | — |
Countries
China
Contacts
Public ContactHongmei Jing
Peking University Third Hospital
Outcome results
None listed