acute circulatory failure
Conditions
Interventions
Gold Standard:Fluid responsiveness was defined as an increase > 10% in SV (measured by TTE) after PLR maneuver
Index test:Decrease in pulse pressure variations after passive leg raising
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Acute circulatory failure in patients transferred to the ICU after surgery: systolic blood pressure less than 90 mmHg, mean arterial pressure less than 65 mmHg (or need norepinephrine for maintenance); 2. Urine output is less than 0.5 ml/kg per hour and lasts for more than 2 hours; 3. Lactic acid > 2 mmol/L; 4. Tachycardia, heart rate greater than 100 beats/min; 5. Skin mottling.
Exclusion criteria
Exclusion criteria: 1. Age < 18 years old; 2. Left ventricular (LV) dysfunction (ejection fraction < 40%); 3. Intracranial hypertension, active bleeding, intra-abdominal hypertension, arrhythmia, lower limb disability; 4. Pregnant women; 5. PLR manipulation contraindications; 6. The echocardiogram cannot be obtained, and the echo is not clear.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pulse pressure variation; | — |
Secondary
| Measure | Time frame |
|---|---|
| central venous pressure;mean arterial pressure;stroke volume; | — |
Countries
China
Contacts
Public ContactJin Xie
The First Affiliated Hospital of Soochow University
Outcome results
None listed