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Clinical study of anesthetization by remimazolam tosilate combined with butorphanol tartrate for polypectomy during painless colonoscopy

Clinical study of anesthetization by remimazolam tosilate combined with butorphanol tartrate for polypectomy during painless colonoscopy

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060361
Enrollment
Unknown
Registered
2022-05-29
Start date
2022-05-17
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with intestinal polyps

Interventions

Experimental group:remimazolam tosylate
Control group:propofol

Sponsors

The First Affiliated Hospital of Shantou University Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Receive elective intestinal polypectomy; 2. The medical history, signs, auxiliary examination and other information are complete; 3. Age 18-80 years old, gender is not limited; 4. BMI 18-28 kg/m2; 5. Understand and voluntarily participate in the research, and sign the informed consent; 6. The ASA classification is I-II level.

Exclusion criteria

Exclusion criteria: 1. History of allergy to benzodiazepines, butorphanol tartrate, propofol; 2. Infection at the injection site; 3. Suffering from uncontrolled hypertension, diabetes, heart failure and other chronic diseases; 4. Hypovolemia, shock or coma; 5. Suffering from serious system diseases such as heart, lung, blood, liver and kidney; 6. Mental or nervous system problems, communication barriers and unable to cooperate; 7. History of drug abuse and alcoholism; 8. Women who are pregnant or breastfeeding; 9. It is difficult to maintain normal vital signs during the operation, or serious complications occur and need to be transferred to the ICU; 10. Participated in a drug clinical trial as a subject within the past 3 months.

Design outcomes

Primary

MeasureTime frame
hypotension;

Secondary

MeasureTime frame
propofol consumption;

Countries

China

Contacts

Public ContactWei Sun

The First Affiliated Hospital of Shantou University Medical College

md.sunwei@gmail.com+86 13580579456

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026