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Clinical study of low-dose esketamine combined with propofol for pediatric painless gastroenteroscopy

Clinical study of low-dose esketamine combined with propofol for pediatric painless gastroenteroscopy

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060345
Enrollment
Unknown
Registered
2022-05-29
Start date
2022-05-16
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastroscopy

Interventions

Experimental group:esketamine

Sponsors

Beijing Children's Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Years to 25 Years

Inclusion criteria

Inclusion criteria: 1. Subjects aged 8-18 years; 2. American Society of Anesthesiologists (ASA) risk score I-II; 3. BMI 18-25 kg/m2; 4. Children receiving painless gastroenteroscopy; 5. Before the start of any activities related to the trial, the subject's legal guardian signs the informed consent, has a full understanding of the purpose and significance of the trial, and is willing to abide by the trial protocol.

Exclusion criteria

Exclusion criteria: 1. Allergy to the study drug; 2. Children with serious risk of elevated blood pressure or intracranial pressure; 3. Patients with poorly controlled or untreated hypertension; 4. Children with untreated or undertreated hyperthyroidism (hyperthyroidism); 5. Children with known congenital heart disease and cardiovascular and cerebrovascular diseases; 6. Children with a history of elevated intraocular pressure or puncture eye injury; 7. Children with a history of asthma; 8. Children with mental system diseases and cognitive dysfunction; 9. Children with uncontrolled epilepsy; 10. Subjects who opt out of participation.

Design outcomes

Primary

MeasureTime frame
Intraoperative propofol dose;

Secondary

MeasureTime frame
Postoperative awakening time of the child;Number of intraoperative body movements;Postoperative pain score;Incidence of adverse reactions;

Countries

China

Contacts

Public ContactGao Zhengzheng

Beijing Children's Hospital, Capital Medical University

sunbrightangel@sina.com+86 15811212551

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026