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Study on the prevention and treatment of Helicobacter pylori infection with probiotics

Study on the prevention and treatment of Helicobacter pylori infection with probiotics

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060330
Enrollment
Unknown
Registered
2022-05-28
Start date
2022-06-06
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infection of Helicobacter pylori

Interventions

Experimental group:Lactobacillus reuteri

Sponsors

Beijing You'an Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Healthy adults aged 18-60 years, male or female; 2. 13C-Urea breath test or gastric mucosal tissue rapid urease test (RUT) identified as Hp (+), but according to the investigator's judgment whether eradication treatment is required; 3. Have not taken anti-inflammatory drugs or antibiotics in the past 3 months; 4. Ability to understand the learning requirements, and promise to cooperate with the research during the entire experiment period; 5. No history of food allergy and intolerance, no history of haemorrhage; 6. The patient is informed of the purpose of the experiment, agrees to participate in the experiment, provides a basic survey form and signs the consent form; 7. No previous anti-pyloric treatment.

Exclusion criteria

Exclusion criteria: 1. History of gastrointestinal surgery (except appendectomy); 2. Allergy to triple antibiotics or any contraindication eradication treatment; 3. Pregnant or lactating women; 4. Any history of serious diseases (severe cardiovascular, endocrine, liver and kidney dysfunction, etc.) before the eradication of Helicobacter pylori treatment; 5. Patients will also be excluded if they have taken probiotics, antibiotics or research products in the month before inclusion; 6. Having mental illness, which may lead to difficulties in cooperation; 7. Patients who lack self-judgment ability; 8. Alcohol or drug abusers; 9. Subjects participating in other clinical trials; 10. The purpose of the researcher's notification to the researcher; 11. Those who do not meet the research requirements or the researchers believe that they should not participate in the research.

Design outcomes

Primary

MeasureTime frame
13C breath test;

Secondary

MeasureTime frame
Blood biochemical examination;Fecal sample;

Countries

China

Contacts

Public ContactZhang Yuening

Beijing Institute of Nutrient Sources Co., Ltd.

amyrie@163.com+86 10 83997599

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026