perinatal depression
Conditions
Interventions
Control group:After the fetus is delivered and the umbilical cord is clipped, intravenous injection of normal saline 0.1 mg/kg
Experimental group:After the fetus was delivered and the umbilical cord was clipped, intravenous esketamine 0.5 mg/kg was administered
Sponsors
The First Affiliated Hospital of USTC Anhui Provincial Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 38 Years
Inclusion criteria
Inclusion criteria: 1. The parturient is voluntary and signs the informed consent; 2. ASA: Level II-III; 3. Planned cesarean section 4. Maternal age: 20 years old 80 x 10^9/L, no obvious abnormality in coagulation function, or PT prolongation < 3 s, APTT prolongation < 10 s.
Exclusion criteria
Exclusion criteria: 1. Psychoneurotic drugs have been used before surgery; 2. Patients with serious or unstable heart, liver, kidney, endocrine, blood, and other internal diseases; 3. Inability to independently understand and complete the contents of the scale; 4. Those with severe depressive symptoms (such as suicidal ideation) require immediate antidepressant treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Edinburgh Postnatal Depression Scale (EPDS); | — |
Countries
China
Contacts
Public ContactLizhen Wang
The First Affiliated Hospital of USTC Anhui Provincial Hospital
Outcome results
None listed