The application study of detecting dynamic variation characteristics of early childhood caries based on multi-omics biomarkers

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200060286

Enrollment

Unknown

Registered

2022-05-26

Start date

2022-06-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental caries

Interventions

Baseline caries group:None

Baseline caries free group:None

Eligibility

Sex/Gender

All

Age

3 Years to 4 Years

Inclusion criteria

Inclusion criteria: A 3-year-old child who meets the following requirements: 1. Without systemic diseases, able to cooperate with sampling and treatment; 2. No mucosal lesions such as ulcers or maxillofacial surgical diseases in the oral cavity; 3. No upper respiratory tract diseases such as colds, tonsillitis, or taking antibiotics within the past 1 month; 4. No local oral fluoride use experience in the past 1 month.

Exclusion criteria

Exclusion criteria: 1.Children who cannot cooperate with sampling or caries treatment; 2. Identify children who cannot complete the 6-month follow-up process.

Design outcomes

Primary

Measure	Time frame
Constitution and function of proteome / peptidome;Structure and function of microbiome;ICDAS code for caries status;	—

Countries

China

Contacts

Public ContactXiangyu Sun

Peking University School and Hospital of Stomatology

allon627@163.com+86 15652312025

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026