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Effects of perioperative transauricular vagus nerve electrical stimulation on postoperative delirium, postoperative cognitive dysfunction and chronic postsurgical pain in patients undergoing knee replacement

Effect of vagus nerve electrical stimulation on prognosis of elderly patients undergoing surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060266
Enrollment
Unknown
Registered
2022-05-24
Start date
2022-05-24
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative delirium, postoperative cognitive dysfunction and chronic postsurgical pain

Interventions

Control group:Pseudo stimulus
Ta-VNS group: transauricular vagus nerve stimulation

Sponsors

Xuzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. 50-80 years; 2. ASA level I and II; 3. Perform elective knee or hip replacement surgery.

Exclusion criteria

Exclusion criteria: 1. The score of the Simplified Mental State Scale (MMSE) is35; 7. Taking antidepressant drugs; 8. ASA>?.

Design outcomes

Primary

MeasureTime frame
Postoperative cognitive function;postoperative delirium;postsurgical pain;—

Countries

China

Contacts

Public ContactYangzi Zhu

Xuzhou Central Hospital

zhuyz@188.com+86 15862149539

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026