perioperative neurocognitive disorders
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA Level I-III; 2. Junior high school or above; 3. Stable blood pressure control in hypertensive patients; 4. Be able to cooperate with music therapy; 5. The preoperative simple intelligence state examination scale score >= 24 points; 6. The Ramsay sedation score before surgery was 2 points.
Exclusion criteria
Exclusion criteria: 1. Sinus bradycardia or sinus tachycardia; 2. Lack of awareness; 3. Alzheimer's disease; 4. Mental illness; 5. History of intracranial surgery; 6. Hearing impairment or wearing hearing aids; 7. Taking psychotropic drugs or opioids for a long time; 8. Excessive drinking for a long time; 9. Gastrointestinal ulcer; 10. Active gastrointestinal bleeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mini-mental state examination scores;Ramsay scores;inflammatory factor; | — |
Secondary
| Measure | Time frame |
|---|---|
| Arterial mean pressure, MAP;Heart rate, HR; | — |
Countries
China
Contacts
Fudan University Pudong Medical Center: Shanghai Pudong Hospital