Irritable Bowel Syndrome
Conditions
Interventions
Test group:None
Control group:None
Sponsors
Department of Gastroenterology, China-Japan Friendship Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Diarrhoeal irritable bowel syndrome conforming to Rome IV diagnostic criteria; 2. Age 18-65 years; 3. Eliminate diarrhea caused by other organic diseases; 4. The laboratory examination results showed that the subjects had no obvious organ function damage; 5. No abnormality is found in colonoscopy.
Exclusion criteria
Exclusion criteria: 1. Those suffering from severe heart, lung, kidney and brain insufficiency and multiple organ failure; 2. Patients with low immune function or patients receiving immunosuppressive drugs; 3. Those with mental illness and obvious disturbance of consciousness who cannot cooperate; 4. Those who have evidence of dependence or abuse of alcohol or other substances; 5. Human immunodeficiency virus (HIV) positive; 6. Women who are pregnant or preparing for pregnancy, and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal mucosal metabolites;Intestinal flora;TGR5; | — |
Countries
China
Contacts
Public ContactYanli Zhang
Department of Gastroenterology, China-Japan Friendship Hospital
Outcome results
None listed