allergic rhinitis
Conditions
Interventions
Accelerated group:optimal accelerated scheme
Standard group:standard schem
Sponsors
Xiangya Hospital Central South University
Eligibility
Sex/Gender
All
Age
12 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Sign informed consent; 2. Aged 12-65 years; 3. Moderate to severe IgE mediated allergic rhinitis or rhinoconjunctivitis (with or without allergic asthma) caused by house dust mite allergens; 4. Patients with allergic asthma must be classified as ''well controlled'' under GINA 2020.
Exclusion criteria
Exclusion criteria: 1. General standards such as inability to understand and comply with research requirements, low expected compliance, intellectual disability, etc.; 2. Criteria for immunotherapy such as anaphylactic shock by AIT injection in the past, dust mite specific immunotherapy in the past 5 years, etc.; 3. Diseases and health conditions: such as severe acute and chronic diseases, autoimmune diseases, immune deficiencies, severe mental and psychological disorders, etc.; 4. Medication: Use of beta-blockers (topical or systemic), ACE inhibitors, contraindications to epinephrine, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| adverse events;serious adverse events;the number, incidence, duration, type, and intensity of adverse events associated with injection study drugs;the number, incidence, duration, type, and intensity of serious adverse events associated with injection study drugs; | — |
Secondary
| Measure | Time frame |
|---|---|
| changes in laboratory test values before and after treatment;tolerability; | — |
Countries
China
Contacts
Public ContactXie Zhihai
Xiangya Hospital Central South University
Outcome results
None listed