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Clinical observation on the effect of general anesthesia and anesthesia medication on the electrocardiogram of surgical patients

Clinical observation on the effect of general anesthesia and anesthesia medication on the electrocardiogram of surgical patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060189
Enrollment
Unknown
Registered
2022-05-21
Start date
2022-05-10
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dexmedetomidine/antagonist group:Infusion of dexmedetomidine and antagonists
Dexmedetomidine/non-antagonist group:Infusion of dexmedetomidine
Control/antagonist group:Infusion of antagonist drugs
Control/non-antagonism group:None

Sponsors

Zhongda Hospital Affiliated to Southeast University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Aged over 18 years; 2. ASA grading ?~?; 3. BMI 18.0-23.99kg/m^2; 4. The expected duration of the operation is more than 2 hours.

Exclusion criteria

Exclusion criteria: 1. Patients with congenital long QT interval syndrome; 2. Recently taking antiarrhythmic drugs that affect QT interval; 3. Electrolyte disorders (hypokalemia, hypocalcemia, hypomagnesemia, etc.); 4. Organic heart disease, myocardial ischemic heart disease, arrhythmia, atrioventricular block and other heart diseases; 5. Liver function and kidney function damage; 6. History of glaucoma; 7. The patient refused to accept the test.

Design outcomes

Primary

MeasureTime frame
Corrected QT interval/PR interval;—

Countries

China

Contacts

Public ContactXia Jiangyan
jiangyanxia731026@aliyun.com+86 13813806217

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026