The incidence, risk factors and potential biomarkers of silent brain infarct after open, endovascular and hybrid surgery for acute aortic syndrome

the research of silent brain infarct after acute aortic syndrome

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200060168

Enrollment

Unknown

Registered

2022-05-21

Start date

2022-05-10

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute aortic syndrome

Interventions

case series:None

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged between 18 and 80 years; 2. Clearly diagnose thoracic aortic dissection, thoracic aortic aneurysm, intracranial hematoma of thoracic aortic wall, and thoracic aortic ulcer patients requiring surgical treatment; 3. Patients can understand the purpose of the experiment, voluntarily participate and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Previous history of cardiac aortic surgery 2. Previous stroke or cerebral hemorrhage; 3. Due to pacemaker implantation, claustrophobia, weakness and other reasons, head MRI was not performed in the time window after acute and severe thoracic aorta surgery.

Design outcomes

Primary

Measure	Time frame
the incidence of silent brain infarct;cognitive function;protein concentrations in plasma;metabolite concentrations in serum;	—

Countries

China

Contacts

Public ContactHu Jia

West China Hospital, Sichuan University

1725194@qq.com+86 18682560211

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026