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Ubenimex capsules (Bestatin) and chemotherapy for the patients with metastatic breast cancer (MBC): A real-world study

Ubenimex capsules (Bestatin) and chemotherapy for the patients with metastatic breast cancer (MBC): A real-world study

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200060145
Enrollment
Unknown
Registered
2022-05-20
Start date
2022-06-01
Completion date
Unknown
Last updated
2024-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

case series:NA

Sponsors

Zhejiang Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Advanced breast cancer patients who meet the diagnostic criteria for breast cancer and receive standardized first-line chemotherapy; 2. Aged 18-75 years; 3. Ubenimex capsules were used within 7 days before and after the start of this chemotherapy; 4. ECOG score <=1 score; 5. Participate in clinical studies voluntarily and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with unknown immunohistochemistry of ER, PgR and HER2; 2. Patients with severe heart, liver and kidney diseases accompanied by severe functional disorders; 3. Pregnant or lactating patients; 4. Patients with mental or cognitive impairment; 5. Patients who are still in other clinical studies within 1 month; 6. Doctors assessed patients with poor compliance or other ineligibility conditions.

Design outcomes

Primary

MeasureTime frame
Progression-free survival;Quality of life score changes;

Secondary

MeasureTime frame
Overall survival;Improvement of immune function indicators;

Countries

China

Contacts

Public ContactWang Xiaojia

Zhejiang Cancer Hospital

wxiaojia0803@163.com+86 13906500190

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026