Azasetron for the prevention of chronic pain after thoracic surgery

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200060139

Enrollment

Unknown

Registered

2022-05-20

Start date

2022-07-01

Completion date

Unknown

Last updated

2024-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative chronic pain

Interventions

Experimental group:Postoperative analgesic pump with azasetron 20mg

Control group:Normal saline

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients aged 20 to 65 years, ASA grade I to ?, preparing for lung surgery.

Exclusion criteria

Exclusion criteria: 1. The patient has a history of severe heart disease, poorly controlled hypertension, and brain, kidney, lung, and liver diseases; 2. Anyone allergic to azasetron; 3. Any contraindications to lidocaine, ropivacaine, midazolam, sufentanil, cisatracurium, azasetron, propofol, diclofenac sodium; 4. Patients who are using 5HT3 blockers and have pre-existing mental illness.

Design outcomes

Primary

Measure	Time frame
visual analgue scale of pain;	—

Secondary

Measure	Time frame
nausea and vomitting;	—

Countries

China

Contacts

Public ContactGong Xingrui

Xiangyang Center Hospital

gongxrhbxy@sohu.com+86 15071551981

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026