sub-anesthesia dose esketamine for prevention of postoperative pain and anxiety after lumbar surgery

the effect of sub-anesthesia dose esketamine on postoperative pain and anxiety after lumbar surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200060138

Enrollment

Unknown

Registered

2022-05-20

Start date

2022-07-01

Completion date

Unknown

Last updated

2024-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute postoperative pain and anxiety

Interventions

Control group:Normal saline 5mL

Group M:0.3mg/kg esketamine

Group H:0.5mg/kg esketamine

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients aged 20 to 60 years with ASA grade?to ? who are scheduled for lumbar surgery.

Exclusion criteria

Exclusion criteria: 1. The patient has a history of severe heart, brain, kidney, lung, and liver diseases; 2. Patients with refractory hypertension, hyperthyroidism, increased intracranial pressure, cerebral hemorrhage, and glaucoma; 3. Anyone allergic to Esketamine; 4. Any contraindications to lidocaine, ropivacaine, midazolam sufentanil, cisatracurium, toranisetron, propofol, diclofenac sodium; 5. Patients who are using NMDA blockers and who have a pre-existing mental illness.

Design outcomes

Primary

Measure	Time frame
visual analogue of pain without activity;visual analgue of anxiety;visual analgue of anxiety with activity;	—

Secondary

Measure	Time frame
wake up time;postoperative sedation and agitation score;sore thorat;	—

Countries

China

Contacts

Public ContactGong Xingrui

Xiangyang Center Hospital

gongxrhbxy@sohu.com+86 15071551981

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026