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Trajectory of immunosuppression and its association with prognosis in children with severe sepsis

Trajectory of immunosuppression and its association with prognosis in children with severe sepsis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200060133
Enrollment
Unknown
Registered
2022-05-19
Start date
2022-05-19
Completion date
Unknown
Last updated
2024-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

Case series:None

Sponsors

Children's Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: 1. Admitted to the PICU of our hospital, Children's Hospital Affiliated to Chongqing Medical University from April 2022 to April 2024, and diagnosed as severe sepsis and septic shock; 2. In line with the 2005 International Consensus on Childhood Sepsis; 3. Aged >28 days; 4. Informed consent was obtained.

Exclusion criteria

Exclusion criteria: 1. Admitted to our hospital and diagnosed with severe sepsis or septic shock for more than 48 hours; 2. CRRT treatment was performed 72 hours before diagnosis; 3. Autoimmune diseases, HIV infection, tumors, and hematological diseases; 4. Use of immunosuppressant within 3 months prior to admission.

Design outcomes

Primary

MeasureTime frame
Congenital immune cells;Acquired immune cells;—

Countries

China

Contacts

Public ContactXu Feng
Xufeng9899@yahoo.com.cn+86 15320206699

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026