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Safety and efficacy evaluation of early enteral nutrition after duodenal anastomosis in neonates

Safety and efficacy evaluation of early enteral nutrition after duodenal anastomosis in neonates

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060129
Enrollment
Unknown
Registered
2022-05-19
Start date
2022-05-09
Completion date
Unknown
Last updated
2024-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

congenital duodenal obstruction

Interventions

Experimental group:Early feeding after duodenal obstruction
Control group:Routine feeding

Sponsors

Department of Neonatal Surgery, Maternal and Child Health Hospital of Guangdong Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 1 Years

Inclusion criteria

Inclusion criteria: 1. Surgical age is in the neonatal period (1-28 days); 2. Duodenal anastomosis (<=2).

Exclusion criteria

Exclusion criteria: 1. Gestational age less than 28 weeks or weight less than 1500kg; 2. Preoperative diagnosis of serious complications, such as infection, gastrointestinal perforation, NEC, etc.; 3. Combined with congenital intestinal motility disorder; 4. Severe imbalance in the ratio of proximal and distal intestinal tube diameter and abnormal intestinal nerves; 5. Complicated with congenital genetic metabolic disease, chromosome malformation, and serious malformation of other systems; 6. Deaths during the study period, abandonment of treatment, transfers to hospitals, etc.

Design outcomes

Primary

MeasureTime frame
blood routine examination;plasma motilin;serum gastrin;serum albumin;immune globulin;serum transferrin;serum prealbumin;IL-6;high-sensitivity C-reactive protein;

Countries

China

Contacts

Public ContactXiao Shangjie

Guangdong Women and Children Hospital

drsiow@163.com+86 137 2983 2930

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026