benign epilepsy in children with centrotemporal spikes (BECTS)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The age of onset ranged from 2 to 18 years; 2. No neurological abnormalities or mental defects before the onset of the disease; 3. Sleep period mainly partial motor attacks, often accompanied by somatosensory symptoms; 4. Spinous foci were located in the central and temporal regions (Rolandic region), and the interparoxysmal background activity was normal; After a period of follow-up, children meeting any of the following conditions were enrolled in the BECTS variant group when they developed atypical symptoms or EEG: (1) New seizure types (negative myoclonus, atypical absence) and/or oropharyngeal dyskinesia occur during the course of the disease; (2) EEG showed that the localized discharge in the Rolandic region increased significantly in both awake and sleeping periods, and some of the discharge reached the ESES during sleep; (3) Cognitive impairment occurred after the onset of the disease (Wechsler intelligence screening), and patients who did not meet the above three criteria during the follow-up period were enrolled into the BECTS typical group.
Exclusion criteria
Exclusion criteria: Previously known neurological or psychiatric disorders, incomplete clinical data, and lost follow-up during follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Age of onset of epilepsy;Intermittent focal slow wave;Multiple asynchronous spike-slow wave lesions;Generalized 3Hz sharp slow wave discharge; | — |
Countries
China
Contacts
Children's Hospital of Chongqing Medical University