osteoporosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Postmenopausal women or men aged over 50 years who have used zoledronic acid 5mg injection at least once for primary osteoporosis; 2. Patients diagnosed with osteoporosis according to the WHO diagnostic criteria for osteoporosis.
Exclusion criteria
Exclusion criteria: 1. Any bone disease other than primary osteoporosis; 2. Patients who received other bisphosphonate anti-osteoporosis drugs in the last 1 year before first zoledronic acid treatment, patients who used other anti-osteoporosis drugs in the last 6 months for more than 2 weeks: Teriparatide, estrogen, selective estrogen receptor modulator, strontium salt, or glucocorticoids in the last 6 months orally or intravenously for more than 3 months; 3. New diseases that affect bone metabolism after treatment with perzoledronic acid or drugs that affect bone metabolism.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Type 1 tropocollagen N - terminal propeptide;Type 1 procollagen carboxy-terminal peptide cross-linked peptide;Vitamin D;Blood calcium;Phosphorus in blood;Alkaline phosphatase;Bone density; | — |
Countries
China
Contacts
Jiangxi Provincial People's Hospital