post stroke depression (PSD)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Outpatient or inpatient patients aged 50-70 years, no gender limit, clinically diagnosed with first-stage ischemic stroke, meeting the stroke diagnostic criteria of the 2018 Chinese Guidelines for the Diagnosis and Treatment of acute Ischemic Stroke, and having more than one confirmed head CT/MRI examination results; 2. Meet the diagnostic criteria for depression of the 4th edition of Chinese Classification and Diagnosis of Mental Disorders (CCMD-4), and the total score of Hamilton Depression Scale 17 (HAMD-17) is 7 or above; 3. No history of other mental diseases or brain trauma; 4. No comprehension disorder, obvious aphasia and other serious complications of stroke; 5. Patients or their guardians give informed consent to the relevant contents of this experiment and sign the informed consent voluntarily.
Exclusion criteria
Exclusion criteria: 1. Progressive stroke; 2. A history of SSIRs and other antidepressants, with Grade III or above cardiac function (NYHY criteria); 3. Craniocerebral trauma, surgical history, or auxiliary devices such as intracranial metal implants, cardiac pacemakers, and ear AIDS; 4. During pregnancy and lactation; 5. Accompanied by tumor, severe infection and other serious complications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction rate of 17-item Hamilton Depression Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mini Mental State Examination; | — |
Countries
China
Contacts
The Second Affiliated Hospital of Xinxiang Medical University