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Efficacy of high-precision transcranial direct current stimulation in the treatment of post-stroke depression

Efficacy of high-precision transcranial direct current stimulation in the treatment of post-stroke depression

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060104
Enrollment
Unknown
Registered
2022-05-18
Start date
2022-06-01
Completion date
Unknown
Last updated
2024-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post stroke depression (PSD)

Interventions

Intervention group:HD-tDCS + drug treatment

Sponsors

The Second Affiliated Hospital of Xinxiang Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Outpatient or inpatient patients aged 50-70 years, no gender limit, clinically diagnosed with first-stage ischemic stroke, meeting the stroke diagnostic criteria of the 2018 Chinese Guidelines for the Diagnosis and Treatment of acute Ischemic Stroke, and having more than one confirmed head CT/MRI examination results; 2. Meet the diagnostic criteria for depression of the 4th edition of Chinese Classification and Diagnosis of Mental Disorders (CCMD-4), and the total score of Hamilton Depression Scale 17 (HAMD-17) is 7 or above; 3. No history of other mental diseases or brain trauma; 4. No comprehension disorder, obvious aphasia and other serious complications of stroke; 5. Patients or their guardians give informed consent to the relevant contents of this experiment and sign the informed consent voluntarily.

Exclusion criteria

Exclusion criteria: 1. Progressive stroke; 2. A history of SSIRs and other antidepressants, with Grade III or above cardiac function (NYHY criteria); 3. Craniocerebral trauma, surgical history, or auxiliary devices such as intracranial metal implants, cardiac pacemakers, and ear AIDS; 4. During pregnancy and lactation; 5. Accompanied by tumor, severe infection and other serious complications.

Design outcomes

Primary

MeasureTime frame
Reduction rate of 17-item Hamilton Depression Scale;

Secondary

MeasureTime frame
Mini Mental State Examination;

Countries

China

Contacts

Public ContactZhang Fuping

The Second Affiliated Hospital of Xinxiang Medical University

zhangfuping2141@163.com+86 18838200543

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026