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Efficacy and safety of dexmedetomidine combined with ropivacaine for anterior serratus muscle block in children underdoing ear reconstruction after costal cartilage harvest

Efficacy and safety of dexmedetomidine combined with ropivacaine for anterior serratus muscle block in children underdoing ear reconstruction after costal cartilage harvest

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060089
Enrollment
Unknown
Registered
2022-05-18
Start date
2022-07-01
Completion date
Unknown
Last updated
2024-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group A:Serratus anterior plane block (ropivacaine)
Group B:Serratus anterior plane block (ropivacaine + dexmedetomidine)

Sponsors

Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 12 Years

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists Physical status I-II, aged 5-12 years, with body mass index (BMI) of 19-25, scheduled for external ear reconstruction with costal cartilage graft in our hospital (Three pieces of cartilage (6th, 7th, 8th rib) were used).

Exclusion criteria

Exclusion criteria: 1. A history of long-term use of analgesics (e.g., opioids, acetaminophen, or nonsteroidal anti-inflammatory drugs); 2. History of abnormal coagulation; 3. Allergic to the proposed drug; 4. Skin infection at the puncture site of nerve block; 5. Patients with less or more than 3 costal cartilages; 6. Patients with speech and mental disorders and unable to complete pain score and postoperative recovery quality score.

Design outcomes

Primary

MeasureTime frame
15-item Quality of Recovery Rating Scale (QoR-15) Score;

Secondary

MeasureTime frame
Rest, coughing pain scores;Dosage of sufentanil analgesic pump within 24 hours;Duration of analgesia;Use of oral remedial analgesics;Opioid side effects;Complications associated with nerve block;First time out of bed;Satisfaction of patient and surgeon;Ear numeric rating method pain score;Ramsay score;Intraoperative blood pressure;Intraoperative dosage of propofol;Boezaart surgical field score;Cough score during extubation;Extubation agitation score;The total length of harvesting cartilage;Surgery duration;Length of stay;Duration of post-anesthesia care unit (PACU) stay;Extubation duration;Heart rate;

Countries

China

Contacts

Public ContactChen Chunmei

Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

chunmeichen2008@163.com+86 18611612186

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026