Effect of bilateral paravertebral nerve block on cognitive function in elderly patients undergoing radical gastrectomy for gastric cancer: a prospective randomized double-blind controlled trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200060088

Enrollment

Unknown

Registered

2022-05-18

Start date

2019-01-01

Completion date

Unknown

Last updated

2024-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Cognitive Dysfunction (POCD)

Interventions

Group PVB :Bilateral paraspinal thoracic block was performed

Group C:None

Eligibility

Sex/Gender

All

Age

65 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients undergoing radical gastrectomy under elective general anesthesia, no gender limit,aged 65-80 years, ASA grade II to III.

Exclusion criteria

Exclusion criteria: 1. Operation time < 2 hours; 2. MMSE score <26; 3. History of preoperative chemotherapy or radiotherapy; 4. Previous history of abdominal surgery; 5. A history of long-term use of opioids or neuropsychiatric drugs; 6. A history of neurological disorders such as Alzheimer's disease, Parkinson's disease, or cognitive impairment; 7. Postoperative ICU; 8. Hearing or speech impairment; 9. Patients with coagulation disorders; 10. Skin infection at the puncture site; 11. Allergy to any drugs used in this study; 12. The patient refused to continue to participate in the study.

Design outcomes

Primary

Measure	Time frame
Mini Mental Status Examination Score;	—

Secondary

Measure	Time frame
Neuron-specific enolase;	—

Countries

China

Contacts

Public ContactQi Fuwei

The First People's Hospital of Taicang

qfw2022@163.com+86 18915678639

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 17, 2026