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A study of the correlation between vestibular function and depressive states and changes in white matter in patients with persistent postural-perceptual dizziness (PPPD)

A study of the correlation between vestibular function and depressive states and changes in white matter in patients with persistent postural-perceptual dizziness (PPPD)

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200060087
Enrollment
Unknown
Registered
2022-05-18
Start date
2022-09-01
Completion date
Unknown
Last updated
2024-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Persistent posturality-perceptual dizziness (PPPD)

Interventions

Case series:None

Sponsors

Xinxiang Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 40-75 years; 2. Meet the diagnostic criteria for PPPD (in accordance with the draft diagnostic criteria for the 11th edition of the International Classification of Diseases); 3. Complete head MRI and other related examinations; 4. Can cooperate to complete various scales; 5. Obtain informed consent from patients and their families, and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with other diseases that may involve the central nervous system, such as cerebrovascular disease, multiple sclerosis, optic neuromyelitis, thyroid related diseases, Parkinson's disease and Parkinson's syndrome, vitamin deficiency, etc.; 2. History of poison use and history of hypoxia; 3. Other diseases that may cause leucoencephalopathy, such as inflammatory demyelinating diseases and genetically related leucoencephalopathy; 4. Patients suffering from end-stage diseases, such as malignant tumors and uremia; 5. Severe cardiac, liver or renal insufficiency; 6. Have definite mental illness, such as schizophrenia; 7. A long history of psychotropic drug use.

Design outcomes

Primary

MeasureTime frame
Degree of depression;White matter lesions;

Countries

China

Contacts

Public ContactGui Yongkun
guiyongkun@126.com+86 15237310973

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026