Cardiovascular disease
Conditions
Interventions
experimental group:Dexmedetomidine
control group:Normal saline
Sponsors
Tianjin First Center Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. The anesthesia grade (ASA grade) was II ~ IV; 2. Cardiac function grade II to III; 3. No obvious abnormality of heart, lung, liver and kidney function before operation.
Exclusion criteria
Exclusion criteria: 1. Allergic to dexmedetomidine hydrochloride; 2. Second pancreas or kidney transplantation; 3. Patients who have taken sedatives for a long time and have a history of mental illness; 4. History of severe arrhythmias such as bradycardia and degree III atrioventricular block; 5. Preoperative encephalopathy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| troponin I;creatine kinase isoenzyme;TNF-a;IL-6;cardiovascular events;ICU stay time; | — |
Countries
China
Contacts
Public ContactYu Wenli
Outcome results
None listed