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Optimization of intervention strategies for persistent atrial fibrillation

Optimization of intervention strategies for persistent atrial fibrillation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060075
Enrollment
Unknown
Registered
2022-05-18
Start date
2019-01-01
Completion date
Unknown
Last updated
2024-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial fibrillation

Interventions

Group ANAT:Anatomic directed ablation
Group EGM:Potential directed ablation
Group EXT:Combined potentio-anatomy guidance for ablation

Sponsors

Shanghai Chest Hospital, Shanghai Jiao Tong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-80 years; 2. Diagnosed as persistent atrial fibrillation according to the latest clinical guidelines; 3. Ineffective or intolerable to >=1 antiarrhythmia drug treatment.

Exclusion criteria

Exclusion criteria: 1. Uncontrolled congestive heart failure; 2. History of severe valve disease and/or prosthetic valve replacement; 3. Myocardial infarction or stroke within 6 months; 4. Severe congenital heart disease; 5. EF <40%; 6. Contrast agent allergy; 7. The use of anticoagulant drugs is contraindicated; 8. Severe lung disease; 9. Left atrial thrombus confirmed by preoperative esophageal ultrasound; 10. Contraindications for cardiac catheterization; 11. Atrial fibrillation ablation; 12. The presence of an implantable cardioverter-defibrillator; 13. Have performed any cardiac surgery within 2 months; 14. Poor general health; 15. Life expectancy < 6 months.

Design outcomes

Primary

MeasureTime frame
intraoperative termination rate of atrial fibrillation;postoperative atrial fibrillation recurrence rate;postoperative atrial tachycardia/atrial flutter recurrence rate;adverse event rate;

Countries

China

Contacts

Public ContactLiu Xu

Shanghai Chest Hospital, Shanghai Jiao Tong University

shchestcardiology@163.com+ 86 21 62821990

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026