Infertility
Conditions
Interventions
Intervention group:personalized embryo transfer according to ERA test results
Control group:embryo transfer according to clinical standard practice
Sponsors
Renji Hospital, Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 39 Years
Inclusion criteria
Inclusion criteria: 1. >=3 embryo transfer failures after transfer of at least three good-quality embryos; 2. The woman was under the age of 40 years old when the eggs are retrieved; 3. There are >=1 good-quality blastocysts that can be transferred(D5/D6); 4. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Uterine diseases that clearly affect the shape of the uterine cavity or endometrial receptivity, such as uterine malformation, submucosal fibroids, intramural fibroids protruding into the uterine cavity, history of endometrial tuberculosis and endometrial hyperplasia, untreated hydrosalpinx and intrauterine adhesion etc.; 2. Chromosomal abnormalities in either spouse; 3. Recurrent miscarriage (>= 2 clinical pregnancy miscarriages); 4. Endomembrane <6mm on the day of transformation; 5. Those with contraindications to endometrial scratching, pregnancy or assisted reproductive technology.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| live birth rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| biochemical pregnancy rate;clinical pregnancy rate;ongoing pregnancy rate;pregnancy loss rate;displace rate of implantation window;pregnancy and perinatal complication;birth weight;congenital anomalies; | — |
Countries
China
Contacts
Public ContactSun Yun
Renji Hospital, Shanghai Jiaotong University School of Medicine
Outcome results
None listed