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Clinical study of modified neurolysis in the treatment of lower extremity diabetic peripheral neuropathy

Clinical study of modified neurolysis in the treatment of lower extremity diabetic peripheral neuropathy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200060034
Enrollment
Unknown
Registered
2022-05-15
Start date
2022-05-05
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic peripheral neuropathy (DPN)

Interventions

Control group:traditional nerve decompression
Experimental group:modified nerve decompression

Sponsors

Affiliated Hospital of Zunyi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-70 years, no gender limit; 2. Diagnosed with type 2 diabetes mellitus (the inclusion criteria for diabetes are based on the diagnostic criteria for diabetes proposed by the WHO Expert Committee on Diabetes in 2005); 3. Good blood sugar control and normal peripheral vascular condition, indicating good local blood supply; 4. The Tinel sign is positive at the nerve compression site. There is numbness and pain in tapping the nerve in the nerve misshapen area; 5. Patients without serious complications and other serious diseases without absolute contraindications for surgery; 6. Patients were informed and volunteered to participate in this study.

Exclusion criteria

Exclusion criteria: 1. Diabetic ketoacidosis, non-ketotic hyperosmolar coma; 2. Patients with malignant tumor; 3. Pregnant or lactating patients; 4. Other diseases or mental disorders that researchers believe may limit the evaluation of efficacy or follow-up of patients, making it difficult for the study to be completed successfully; 5. Those considered unsuitable by researchers.

Design outcomes

Primary

MeasureTime frame
motor nerve conduction velocity;

Secondary

MeasureTime frame
Pain Visual Score;two-point discrimination;Toronto Neuropathy Score;

Countries

China

Contacts

Public ContactWei Zairong
1299895800@qq.com+86 852 28608340

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026