gastric cancer
Conditions
Interventions
Gold Standard:Gastroscope and capsule endoscopy
Index test:Li's gastric cancer screening scoring system (Questionnaire survey, detection of serum pepsinogen, gastrin-17 and Helicobacter pylori antibody)
Sponsors
Changhai Hospital Affiliated to Navy Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 79 Years
Inclusion criteria
Inclusion criteria: People aged 40 to 79 years without gastrointestinal symptoms, no gender limit, need to sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Within one year since the last gastroscopy; 2. History of subtotal gastrectomy; 3. Take PPI (Esomeprazole, pantoprazole, Rabeprazole, Lansoprazole, etc.) or H2 receptor antagonist (Famotidine, etc.) within 2 weeks; 4. Have one or more of the following symptoms: (1) Iron deficiency anemia within 6 months; (2) Gastrointestinal bleeding (black stool, bloody stool, etc.) within 12 months; (3) Weight loss (weight loss >=4.5Kg within 6 months for reasons other than weight loss); (4) Frequent diarrhea; (5) Difficulty swallowing or choking; (6) Abdominal mass; 5. History of any of the following diseases: esophageal cancer, gastric cancer, colorectal cancer, polyposis, inflammatory bowel disease, malignant tumors of other organs (breast, ovary, uterus, and urinary system, etc.); 6. Imaging, tumor markers and other examinations highly suspect the possibility of cancer; 7. Severe heart, lung, liver and kidney insufficiency, or severe mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pepsinogen I;Pepsinogen II;Gastrin 17;Antibodies to Helicobacter pylori;sensitivity, specificity, accuracy; | — |
Countries
China
Contacts
Public ContactDu Yiqi
Changhai Hospital, Naval Medical University
Outcome results
None listed