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Effects of transverse abdominis plane block and sufentanil on MACBAR of sevoflurane and hemodynamics during pneumoperitoneum stimulation

Effects of transverse abdominis plane block and sufentanil on MACBAR of sevoflurane and hemodynamics during pneumoperitoneum stimulation

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200059993
Enrollment
Unknown
Registered
2022-05-14
Start date
2022-05-20
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecological laparoscopic surgery patients

Interventions

Sevoflurane + TAP group (Group CT):Both sides were given 0.33% ropivacaine 20ml for TAP
Sevoflurane + Sufentanil group (Group CS):0.5ug/kg sufentanil was given intravenously 3min before skin excision
Sevoflurane + TAP group+Sufentanil group (Group TS):Both sides were given 0.33% ropivacaine 20ml for TAP and 0.5ug/kg sufentanil was given intravenously 3min before skin excision

Sponsors

Affiliated Hospital of North Sichuan Medical College
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. ASA I-II; 2. Age 18-65; 3. 100 patients with gynecological laparoscopic surgery were selected.

Exclusion criteria

Exclusion criteria: 1. The patient has a history of cardiopulmonary disease; 2. Abnormal liver and kidney function; 3. Have a history of hypertension, diabetes and stroke; 4. Have a history of alcoholism and drug abuse; 5. Patients with acid-base electrolyte imbalance and blood coagulation disorder before operation; 6. Those who have recently taken drugs that affect the cardiovascular system and adrenergic response; 7. Pregnant patients; 8. Patients who are allergic to local anesthetics.

Design outcomes

Primary

MeasureTime frame
minimal alveolar concentration of blocking adrengic response(MACBAR);Heart rate(HR);Mean arterial blood pressure(MAP);

Secondary

MeasureTime frame
Postoperative abdominal pain Visual Analogue Scale/Score(VAS);

Countries

China

Contacts

Public ContactPingping Jiang

Affiliated Hospital of North Sichuan Medical College

307174907@qq.com+86 15881496034

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026