knee arthroplasty
Conditions
Interventions
two:Qnox monitoring
one:BIS monitoring
Sponsors
anhui provincial hospital
Eligibility
Sex/Gender
All
Age
65 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Patients who plan to undergo knee replacement (including total knee replacement and single condylar replacement); 2. American Association of Anesthesiologists (ASA) grading II - III; 3. Age = 65 years; 4. Preoperative MMSE score = 17 points.
Exclusion criteria
Exclusion criteria: 1. Patients with cognitive impairment, mental illness or dementia before operation; 2. Patients with severe organic diseases (coronary heart disease, bronchial asthma, severe hypertension, severe blood system dysfunction, liver and kidney function, and electrolyte abnormalities); 3. Have a long history of abuse of sedatives or analgesics; 4. Those who have participated in clinical trials of other drugs in the past 4 weeks.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| C-reactive protein;Postoperative Recovery Quality Scale-15; | — |
Primary
| Measure | Time frame |
|---|---|
| postoperative delirium;Postoperative pain score; | — |
Countries
China
Contacts
Public ContactWang sheng
Anhui provincial hospital
Outcome results
None listed