preterm birth
Conditions
Interventions
Exposure:Comprehensive treatment system following to practice guideline
Controlled:Regular comprehensive treatment system
Sponsors
West China Second University Hospital, Sichuan University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Those who visit prenatal care regularly and plan to delivery at study sites, will sign the inform consent form before participating in this study; 2. Gestational age should be diagnosed between 24- 34+6weeks by sonography; present with irregular or regular contractions, regardless of cervical shortening or dilation/ rupture of membrane/bloody vaginal discharge; 3.Inpatient treatment,including tocolysis, is needed.
Exclusion criteria
Exclusion criteria: 1. Patients who clearly indicated that they did not give birth in the research center; 2. There are drug contraindications such as ritodrine hydrochloride, nifedipine, atoxiban, magnesium sulfate and dexamethasone; 3. Pregnancy = 35 weeks or<24 weeks; 4. The following conditions occur during pregnancy: fetal malformation/chromosome abnormality; Or patients with iatrogenic premature delivery indications such as complete placenta previa, vascular previa, severe pre-eclampsia, monochorionic monoamniotic sac twins; 5. People with serious basic diseases, such as cardiovascular disease, liver and kidney function impairment, immune deficiency, diabetes, hypertension, tumor disease, etc; 6. Those with mental and intellectual disorders who cannot cooperate with the questionnaire; 7. Participated in any drug or nutrition clinical trial (pre-marketing drug clinical trial) from 3 months before pregnancy to pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall preterm birth rate; | — |
Countries
China
Contacts
Public ContactXinghui Liu
West China Second University Hospital, Sichuan University
Outcome results
None listed