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Bone damage in obese patients after bariatric surgery based on dual energy X-ray absorptiometry, quantitative CT and MRI bone marrow fat measurement

Bone damage in obese patients after bariatric surgery based on dual energy X-ray absorptiometry, quantitative CT and MRI bone marrow fat measurement

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200059977
Enrollment
Unknown
Registered
2022-05-14
Start date
2022-05-01
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obesity

Interventions

non T2MD group:N/A

Sponsors

Beijing Friendship Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-65 years; 2. It meets the indications for weight-loss metabolism surgery and has not yet undergone weight-loss metabolism surgery; 3. Type 2 diabetes group: type 2 diabetes was diagnosed more than half a year ago, HbA1c>7%.

Exclusion criteria

Exclusion criteria: 1. There are contraindications to weight loss and metabolism surgery; 2. There are thyroid or parathyroid diseases, chronic kidney disease and tumor diseases; 3. It is accompanied by other diseases of skeletal muscle system, such as rheumatoid arthritis; 4. There are contraindications to DXA, CT and MR examinations, such as: pregnant and lactating women, metal implants in their bodies, such as cardiac pacemakers, metal foreign bodies in the eyeball, claustrophobia, etc; 5. Use of drugs that affect bone metabolism, such as bisphosphonates, calcitonin, parathyroid hormone analogues, and long-term hormone application history; 6. Unable to understand the research protocol and refused to sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
height;weight;bone mineral density;body composition;bone marrow adipose;blood glucose;

Countries

China

Contacts

Public ContactGuan Wenmin

Beijing Friendship Hospital, Capital Medical University

guanwenmin@126.com+86 18811121612

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026