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Personalized PEEP and degree of variation of patients undergoing cardiac valve replacement

Personalized PEEP and degree of variation of patients undergoing cardiac valve replacement

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200059974
Enrollment
Unknown
Registered
2022-05-14
Start date
2022-05-01
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pulmonary complications

Interventions

1:Individualized peep value according to minimum driving pressure titration
2:Individual peep value of maximum lung compliance titration

Sponsors

Wannan Medical College, Yijishan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing cardiac valve replacement; 2. Age 35-70; 3. ASA II - III; 4.BMI<28kg/m2.

Exclusion criteria

Exclusion criteria: 1. There was serious pulmonary infection before operation; 2. Atelectasis; 3. Intracranial hypertension; 4. Pneumothorax; 5. Bronchopleural fistula; 6. Preoperative PaO2 < 60 mmHg; 7. Pregnancy; 8. Chronic obstructive pulmonary disease (COPD); 9. Secondary thoracotomy; And refused to participate in the study.

Design outcomes

Primary

MeasureTime frame
positive end-expiratory pressure;Postoperative pulmonary complications;—

Secondary

MeasureTime frame
Degree of variation of PEEP;—

Countries

China

Contacts

Public ContactGuo Wenjun
Gwj8581@sina.com+86 13605532244

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026