knee osteoarthritis
Conditions
Interventions
Knee osteoarthritis mild pain group:without
Knee osteoarthritis moderate pain group:without
Healthy control:without
Sponsors
Fujian University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: Subjects with knee osteoarthritis: 1. The age is 50-80 years old; 2. Diagnosed as knee osteoarthritis; 3. Kellgren&Lawrence is rated 2 or 3; 4. The average pain score of NRS in the past 24 hours is 1-6 points; 5. Body mass index (BMI) = 30 kg/?; 6. Right-handed; 7. Have certain reading comprehension and communication skills, and can cooperate to complete the experiment; 8. Sign the informed consent form and participate voluntarily. Healthy subjects: 1. Age: 50-80 years; 2. Body mass index (BMI) = 30 kg/?; 3. Right-handed; 4. Have certain reading comprehension and communication skills, and can cooperate to complete the experiment; 5. Sign the informed consent form and participate voluntarily.
Exclusion criteria
Exclusion criteria: Subjects with knee osteoarthritis: 1. History of knee surgery (such as arthroscopic surgery) in the past 6 months or intra-articular corticosteroid injection in the past 3 months; 2. Knee joint pain caused by other inflammatory diseases such as rheumatoid arthritis; 3. Primary or secondary muscular diseases (such as idiopathic inflammatory myopathy, progressive muscular dystrophy, glycogen storage, etc.); 4. Beck Depression Inventory-II (BDI-II) = 14 points; 5. Severe knee joint deformity; 6. Abnormal mental state, unable to be autonomous, or unable to cooperate with research intervention and staff; 7. Serious knee injury leads to knee instability or lower limb force line deviation; 8. Serious cardio-cerebrovascular disease, musculoskeletal system disease or other contraindications that are not allowed to participate in the study; 9. Hemorrhagic disease. Healthy control group: 1. Primary or secondary muscular diseases (such as idiopathic inflammatory myopathy, progressive muscular dystrophy, glycogen storage, etc.); 2. Abnormal mental state, unable to be autonomous, or unable to cooperate with research intervention and staff; 3. Serious cardio-cerebrovascular disease, musculoskeletal system disease or other contraindications that are not allowed to participate in the study; 4. Long-term chronic pain history; 5. Beck Depression Inventory-II (BDI-II) = 14 points.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional near infrared spectroscopy imaging; | — |
Secondary
| Measure | Time frame |
|---|---|
| range of motion;Pain scores of Western Ontario and McMaster Universities Osteoarthritis Index;Knee Injury and Osteoarthritis Outcome Score;numerical rating scale;Beck Depression Inventory-II scores; | — |
Countries
China
Contacts
Public ContactLiu Xuefeng
College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine
Outcome results
None listed