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Effect of augmented renal clearance on sulbactam concentration in critically ill patients

Effect of augmented renal clearance on sulbactam concentration in critically ill patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200059955
Enrollment
Unknown
Registered
2022-05-14
Start date
2022-05-01
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infection

Interventions

2:None

Sponsors

Shandong Provincial Hospital Affiliated to Shandong First Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Between the age of 18 and 70; 2. Without previous chronic hepatic or renal insufficiency; 3. Receiving intravenous sulbactam; 4. Written informed consent was obtained from the guardian.

Exclusion criteria

Exclusion criteria: 1. Pregnancy and lactation; 2. Sulbactam use before ICU admission; 3. Sulbactam contraindication; 4. APACHE II > 36 on ICU admission; 5. Neutropenia for more than 1 week or solid organ transplant recipients; 6. Receiving plasmapheresis or renal replacement therapy.

Design outcomes

Primary

MeasureTime frame
T%>MIC > 50%;—

Countries

China

Contacts

Public ContactJiang Jinjiao

Shandong Provincial Hospital Affiliated to Shandong First Medical University

jjjsch@163.com+86 18678877551

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026