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Circulating exosome MicroRNA as an early biomarker and mechanism of action in obesity sarcopenia: A pilot study

Circulating exosome MicroRNA as an early biomarker and mechanism of action in obesity sarcopenia: A pilot study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200059935
Enrollment
Unknown
Registered
2022-05-13
Start date
2022-05-01
Completion date
Unknown
Last updated
2024-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obesity sarcopenia

Interventions

Myopenia obesity group:None

Sponsors

Hainan General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Sign a written informed consent notice; 2. The diagnosis of myopenia obesity is myopenia+obesity.

Exclusion criteria

Exclusion criteria: 1. Have diabetes foot and other diseases that cause lower limb movement disorder; 2. Endocrine diseases such as thyroid dysfunction, Cushing's syndrome, pituitary dysfunction; 3. Various acute and chronic infections and other immune diseases, such as end-stage renal disease, liver failure, heart failure and respiratory failure; Or with malignant tumor or pregnancy; 4. Unable to cooperate in the measurement of walking speed and grip strength; 5. Take anti-osteoporosis drugs, glucocorticoids, thyroid hormones, sex hormones and other drugs; 6. Long-term drinking history, that is, drinking for more than 5 years, or alcohol consumption>140 g/week for men and>70 g/week for women.

Design outcomes

Primary

MeasureTime frame
General clinical data;glucose metabolism;Lipid metabolism;MicroRNA;Exosomes;Bone metabolism;Routine blood;liver function;renal function;electrolyte;

Countries

China

Contacts

Public ContactXian Zhang

Hainan General Hospital

zhangxian0276@163.com+86 18789898068

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026