Effects of combined use of salbutamol/budesonide in thoracic surgery on postoperative myocardial injury (MINS) – A prospective randomized clinical trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200059926

Enrollment

Unknown

Registered

2022-05-13

Start date

2022-05-01

Completion date

Unknown

Last updated

2024-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative myocardial injury

Interventions

Control group :None

Experimental group:Salbutamol/budesonide

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. All patients should be = 45 years old, meet one or more of the following criteria and undergo selective thoracoscopic pneumonectomy; 2. Coronary artery disease history, peripheral artery disease history, stroke history, and the following criteria meet two criteria (= 70 years old, congestive heart failure history, cerebrovascular disease history, diabetes history, hypertension history, smoking history, preoperative creatinine>2.0mg/dL).

Exclusion criteria

Exclusion criteria: 1.Sepsis; 2.Preoperative use of positive inotropic drugs; 3.Severe heart failure (EF<30%); 4.History of asthma; 5.Long-term use of hormone drugs before operation.

Design outcomes

Primary

Measure	Time frame
Myocardial injury after non-cardiac surgery;hsTnT;	—

Secondary

Measure	Time frame
Pulmonary complications;Cardiovascular complications;Lung compliance;30-day postoperative mortality;Visual analogy score;Analgesic dosage;Risk prediction model;	—

Countries

China

Contacts

Public ContactJindong Liu

Affiliated Hospital of Xuzhou Medical University

liujindong1818@163.com+86 13951355136

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026