Alcohol dependence
Conditions
Interventions
Probiotics + conventional drug treatment group:On the basis of conventional drug therapy, probiotic powder 2g, mixed into water or milk, dissolved oral.
Placebo + conventional drug treatment group:On the basis of conventional drug treatment, maltodextrin with the same weight as experimental drug treatment group was mixed into water or milk, dissolved
Sponsors
The Second Affiliated Hospital of Xinxiang Medical College
Eligibility
Sex/Gender
Male
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. 18-60 years, male, right-handed, Han nationality; 2. Education level at primary school or above; 3. Normal vision or corrected vision; 4. Participate voluntarily and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Suffering from other mental diseases; 2. Patients who are allergic to the active ingredients or excipients of this product; 3. Previous history of brain organic disease, pacemaker, gastrointestinal surgery or serious health problems; 4. Previous history of epilepsy; 5. Complicated with serious physical disease; 6. Other drug dependence (except nicotine dependence); 7. Take drugs that affect intestinal flora 30 days before and during admission; 8. Participate in any other alcohol-related research or test within the past 30 days; 9. Use any prescription or over-the-counter drugs that may affect mood or craving for alcohol within the past 30 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal flora; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mental scale;EEG; | — |
Countries
China
Contacts
Public ContactZhang Bingyu
Second Affiliated Hospital of Xinxiang Medical College
Outcome results
None listed