postoperative neurocognitive disorders
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age between 18 and 80; 2.ASA ?-?; 3.Patiens undergo selective non-brain and non-cardiovascular operation; 4.Patiens voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Preoperative MMSE score =23; 2. Have a history of mental illness or nervous system disease; 3. Unable to cooperate in the questionnaire survey, such as language or hearing impairment, cannot communicate in Mandarin or Cantonese, etc. 4. Long-term use of sedatives, or have drug dependence; 5. Patients judged by the researcher to be unsuitable for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score of Mini-Mental State Examination;Score of Confusion Assessment Method;genotype;biomarkers in blood;electroencephalogram; | — |
Secondary
| Measure | Time frame |
|---|---|
| Score of Pittsburgh sleep quality index; | — |
Countries
China
Contacts
The First Affiliated Hospital, Sun Yat-sen University