Adrenal Disease
Conditions
Interventions
Gold Standard:The diagnostic criteria for aldosteronoma (the most important type of unilateral primary aldosteronism) is the "four-corner" criteria proposed by PAPY in 2006, that is, the diagnosis of
Index test:To screen out serum-specific markers that can be prepared to differentiate between aldosterone producing adenoma (APA) and idiopathic hyperaldosteronism(IHA), and to explore their diagnosti
and using the above-screened markers, Preliminary development of a PA typing diagnostic model&
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Selected from patients with aldosterone-producing adenoma (APA) and patients with idiopathic hyperaldosteronism (IHA) in our hospital.
Exclusion criteria
Exclusion criteria: 1. Patients in the primary aldosterone group who did not undergo AVS; 2. Cancer patients with expected life <6 months; 3. Women who are pregnant or breastfeeding; 4. Patients with serious primary diseases such as liver, kidney, hematopoietic system, or abnormal liver function, AST or ALT greater than 2 times the normal value, and creatinine greater than the upper limit of the normal value; 5. Psychiatric patient.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure;Serum potassium;Renin;Aldosterone; | — |
Countries
China
Contacts
Public ContactRen Yan
West China Hospital, Sichuan University
Outcome results
None listed