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The 95% minimum effective oxygen concentration of high flow nasal cannula oxygen therapy for flexible bronchoscopy in children: A biased-coin design up-and-down sequential allocation trial

The 95% minimum effective oxygen concentration of high flow nasal cannula oxygen therapy for flexible bronchoscopy in children: A biased-coin design up-and-down sequential allocation trial

Status
Active, not recruiting
Phases
Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200059885
Enrollment
Unknown
Registered
2022-05-13
Start date
2022-05-16
Completion date
Unknown
Last updated
2024-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypoxemia

Interventions

Hypoxia group:The mask is pressurized to supply oxygen

Sponsors

Children’s Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. Children undergoing fiberbronchoscopy; 2. Oxygen saturation > 90% without oxygen inhalation before surgery; 3. Aged 5 months to 3 years old; 4. ASA grade 1-3.

Exclusion criteria

Exclusion criteria: 1. Skull fracture, facial fracture; 2. Changes in nasal septum or nasal cavity lead to significant obstruction of nasal airflow; 3. There is a risk of reflux aspiration; 4. Difficulty in mask ventilation and intubation; 5. Children who cannot maintain preoperative oxygenation and need supplementary ventilation; 6. Complicated with serious heart disease and brain disease; 7. Platelet count < 50*10^9/L.

Design outcomes

Primary

MeasureTime frame
SPO2;

Secondary

MeasureTime frame
Transdermal carbon dioxide;Time of operation;Recovery times;

Countries

China

Contacts

Public ContactXu Yin

Children’s Hospital of Chongqing Medical University, No.136 Zhongshan Second Road, Yuzhong District, Chongqing, 400014, China

xl63632143@163.com+86 13983409393

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026