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A prospective nested case-control study on the relationship between HE4 and the diagnosis of endometrial cancer and precancerous stages

A prospective nested case-control study on the relationship between HE4 and the diagnosis of endometrial cancer and precancerous stages

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200059862
Enrollment
Unknown
Registered
2022-05-13
Start date
2023-01-01
Completion date
Unknown
Last updated
2024-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometrial cancer and precancerous lesions

Interventions

Gold Standard:Pathological examination results after hysteroscopic curettage
Index test:Serum HE4 value

Sponsors

People's Hospital of Shapingba District, Chongqing
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
35 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged >=35 years, with a history of abnormal uterine bleeding and confirmed by hysteroscopic biopsy as normal proliferative endometrium, benign endometrial hyperplasia, endometrial hyperplasia with atypical and endometrial cancer.

Exclusion criteria

Exclusion criteria: 1. Patients with other endometrial lesions (such as endometrial polyps, submucosal fibroids, etc.); 2. Patients with liver and kidney disease, adnexal disease, uterine fibroids >5cm, other malignant tumors, and a history of radiotherapy and chemotherapy; 3. Unable to perform hysteroscopy to biopsy; 4. Those who refused to participate in this clinical trial or refused to sign the informed consent.

Design outcomes

Primary

MeasureTime frame
Human epididymal protein;

Countries

China

Contacts

Public ContactLi Ning

People's Hospital of Shapingba District, Chongqing

113292934@qq.com+86 15086721542

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026