Postoperative sore throat
Conditions
Interventions
Control group:Normal saline 5.0 ml nebulized
Experimental group:Esketamine aerosol inhalation
Sponsors
Wuhu First People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. ASA grade I-II; 2. Age 18-65 years old, no gender restrictions; 3. The operation was performed in the supine position under general anesthesia, and the estimated operation time was 1 to 3 hours.
Exclusion criteria
Exclusion criteria: 1. Refusal by patients or relatives; 2. Known allergy to the drugs used in the study; 3. There are contraindications to the drugs used in the study; 4. Obvious heart, respiratory, liver or kidney dysfunction; 5. Neuromuscular diseases; 6. Recent sore throat; 7. Patients with expected difficult airway; 8. Having head, neck or oral surgery; 9. Mallampati grade is greater than 2; 10. Pregnant and lactating women; 11. Recent use of non-steroidal anti-inflammatory drugs; 12. Patients with more than two intubation attempts.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure, MAP;Heart Rate (HR);Plasma Esketamine Concentrations;Age;Gender;Body Mass Index;ASA status;Diagnosis;Operation time;Time of anesthesia;Other complications; | — |
Primary
| Measure | Time frame |
|---|---|
| Postoperative sore throat; | — |
Countries
China
Contacts
Public ContactXie Ben-Fa
Wuhu First People's Hospital
Outcome results
None listed