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Clinical study of different concentrations of nasal saline irrigation in the treatment of mild/common COVID-19

Clinical study of different concentrations of nasal saline irrigation in the treatment of mild/common COVID-19

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200059821
Enrollment
Unknown
Registered
2022-05-12
Start date
2022-05-04
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19

Interventions

Control group:No intervention
Experimental group 1:Nasal irrigation with 0.9% saline 250ml twice a day for 4 weeks
Experimental group 2:Nasal irrigation with 1.5% hypertonic saline 250ml twice a day for 4 weeks

Sponsors

Shanghai Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. SARS-CoV-2 infection nucleic acid test positive, according to the "COVID-19 Treatment protocol (Trial Version 9)" diagnosis of mild or ordinary patients; 2. Age >=18; 3. Nasal irrigation ability; 4. Signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant; 2. Suffering from immunosuppressive diseases; 3. Patients participating in other medical trials; 4. People who have negative NUCLEIC acid results for COVID-19 with upper respiratory symptoms; 5. Severe/critical COVID-19 patients; 6. People who cannot answer the phone or access email/Internet; 7. People living with the patients currently participating in the study.

Design outcomes

Primary

MeasureTime frame
The SARS-CoV-2 nucleic acid test was negative;

Secondary

MeasureTime frame
The severity of all the symptoms;The length of time an individual's symptoms resolve;The number of people in the participants' families who developed symptoms;Number of participants who reported side effects of nasal irrigation;Subjective olfactory detection;Questionnaire of olfactory disorders, QOD;

Countries

China

Contacts

Public ContactZhipeng Li

Shanghai Sixth People's Hospital

317411734@qq.com13122752701

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026