Hypocalcemia
Conditions
Interventions
Group A (Preoperative calcitriol and calcium carbonate):Preoperative calcitriol and calcium carbonate
Group B:Preoperative calcium carbonate
Group C (Control group):No preoperative intervention
Sponsors
Tianjin Medical University Cancer Institute and Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Written informed consent signed; 2. Age over 18 years; 3. Initial diagnosis suspicious of bilateral thyroid carcinoma (either by preoperative ultrasonography and/or fine needle aspiration); 4. Planned surgery: total thyroidectomy plus bilateral central compartment neck dissection, with or without various extents of lateral neck dissection.
Exclusion criteria
Exclusion criteria: 1. Preexisting hypercalcemia or any extent of renal dysfunction that impairs metabolism of calcium; 2. Abnormal preoperative PTH level or accompanied parathyroid diseases; 3. History of any form of thyroid surgery or neck dissection; 4. Postoperative pathological examination revealed other than bilateral papillary thyroid carcinoma (e.g., unilateral thyroid cancer or other subtypes of thyroid cancer should be excluded); 5. Patients receiving neck dissection less than bilateral central compartment neck dissection (e.g., unilateral central compartment neck dissection should be excluded irrespective of various co-existing lateral neck dissection).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum calcium level; | — |
Secondary
| Measure | Time frame |
|---|---|
| Symptomatic hypocalcemia;Parathryroid hormone, PTH;Inorganic phosphorus; | — |
Countries
Cnina
Contacts
Public ContactXiangqian Zheng
Tianjin Medical University Cancer Institute and Hospital
Outcome results
None listed