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Effective dose for intravenous remimazolam-induced in general anesthesia with BIS monitoring

Effective dose for intravenous remimazolam-induced in general anesthesia with BIS monitoring

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200059787
Enrollment
Unknown
Registered
2022-05-11
Start date
2022-04-30
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hysteroscopic surgery

Interventions

Group 1:Induction by general anesthesia with 0.1 mg/kg rimazolam.
Group 2:Induction by general anesthesia with 0.2 mg/kg rimazolam.
Group 3:Induction by general anesthesia with 0.3 mg/kg rimazolam.
Group 4:Induction by general anesthesia with 0.4 mg/kg rimazolam.

Sponsors

Hangzhou Women's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-60 years who underwent hysteroscopic surgery; 2. ASA I-II level; 3. Body mass index (BMI) 18-30 kg/m2; 4. Sign the informed consent form, be able to accept the experimental method, and volunteer as a subject.

Exclusion criteria

Exclusion criteria: 1. Hypersensitivity to remimazolam or contraindications to the use of remimazolam; 2. Preoperative disturbance of consciousness or long-term use of analgesics, psychotropic drugs, and alcohol abusers with chronic pain; 3. Sedatives, antiemetics, antipruritic drugs or monoamine oxidase inhibitors or antidepressants were used within 15 days before the operation; 4. Any history of abnormal upper airway airway management or respiratory insufficiency or sleep apnea that may lead to dyspnea.

Design outcomes

Primary

MeasureTime frame
bispectral index, BIS;

Secondary

MeasureTime frame
Sedation score;Blood pressure;Heart rate;

Countries

China

Contacts

Public ContactXiaodong Huang

Hangzhou Women's Hospital

350236963@qq.com+86 15068790428

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026